Due to the genetic nature and complexity of mitochondrial disorders, tailored approaches to treatment and care are essential. Alongside medical management, nutritional strategies can play an important role in supporting energy production, reducing the severity of symptoms, and improving quality of life for adults living with mito.

For people living with mitochondrial disease, regular meals and balanced nutrients can help maintain steady energy and reduce metabolic stress.

Our MitoNutrition hub is designed to provide you with practical, evidence-informed nutrition knowledge to help you better understand how food, hydration, and supplements can support mitochondrial health.

Our MitoNutrition hub is organized into easy-to-navigate chapters. Explore the many topics by selecting the tiles below. Each section dives deeper into key nutrition concepts, practical strategies, and considerations that may help support managing nutrition in mitochondrial disease.

Food can affect symptoms in mitochondrial disease. Some people find that skipping meals, very large meals, or certain foods can trigger fatigue, headaches, or digestive discomfort. Keeping a simple food-and-symptom journal may help identify patterns and guide personalized nutrition strategies.

Nutrition strategies should always be individualized.
Some specialists recommend targeted supplements, often called the mito cocktail, but there is no single standard approach. Because prolonged fasting can increase metabolic stress for some individuals with mito, major diet changes should always be discussed with your specialist.

Read, download or share our MitoNutrition guide for adults below.

Read, download or share our MitoNutrition infographic below.

This resource was developed with the support of an unrestricted education grant from Ultragenyx.